Myosin heavy chain Rabbit Monoclonal Antibody (CAB4963)
- SKU:
- CAB4963
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CMD1S
- CMH1
- MPD1
- MYHCB
- SPMD
- SPMM
- Research Area:
- Cell Biology
Description
Product Name: | Myosin heavy chain Rabbit Monoclonal Antibody |
SKU: | CAB4963 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1200-1400 of human Myosin heavy chain (P12883). |
Sequence: | VAEL GEQI DNLQ RVKQ KLEK EKSE FKLE LDDV TSNM EQII KAKA NLEK MCRT LEDQ MNEH RSKA EETQ RSVN DLTS QRAK LQTE NGEL SRQL DEKE ALIS QLTR GKLT YTQQ LEDL KRQL EEEV KAKN ALAH ALQS ARHD CDLL REQY EEET EAKA ELQR VLSK ANSE VAQW RTKY ETDA IQRT EELE EAKK KLAQ RLQE A |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | CMD1S; CMH1; MPD1; MYHCB; SPMD; SPMM; Myosin heavy chain |
Positive Sample: | Mouse lung,Mouse skeletal muscle,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, myofibril. |
Calculated MW: | 224kDa |
Observed MW: | 250kDa |
Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy. [provided by RefSeq, Jul 2008]
Purification Method: | Affinity purification |
Gene ID: | 4625/4624 |
Clone Number: | ARC1170 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |