MYH9 Rabbit Polyclonal Antibody (CAB0173)
- SKU:
- CAB0173
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | MYH9 Rabbit Polyclonal Antibody |
SKU: | CAB0173 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1711-1960 of human MYH9 (NP_002464.1). |
Sequence: | ANSS GKGA LALE EKRR LEAR IAQL EEEL EEEQ GNTE LIND RLKK ANLQ IDQI NTDL NLER SHAQ KNEN ARQQ LERQ NKEL KVKL QEME GTVK SKYK ASIT ALEA KIAQ LEEQ LDNE TKER QAAC KQVR RTEK KLKD VLLQ VDDE RRNA EQYK DQAD KAST RLKQ LKRQ LEEA EEEA QRAN ASRR KLQR ELED ATET ADAM NREV SSLK NKLR RGDL PFVV PRRM ARKG AGDG SDEE VDGK ADGA EAKP AE |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:1000 - 1:2000 IHC-P,1:50 - 1:100 |
Synonyms: | MHA; FTNS; EPSTS; BDPLT6; DFNA17; MATINS; NMMHCA; NMHC-II-A; NMMHC-IIA; MYH9 |
Positive Sample: | HeLa,Jurkat,LO2,SW480,Mouse liver,Mouse lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, cell cortex, cytoskeleton. |
Calculated MW: | 227kDa |
Observed MW: | 250kDa |
This gene encodes a conventional non-muscle myosin; this protein should not be confused with the unconventional myosin-9a or 9b (MYO9A or MYO9B). The encoded protein is a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain which is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in this gene have been associated with non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness.
Purification Method: | Affinity purification |
Gene ID: | 4627 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |