SMMHC/MYH11 Rabbit Polyclonal Antibody (CAB10827)
- SKU:
- CAB10827
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | SMMHC/MYH11 Rabbit Polyclonal Antibody |
SKU: | CAB10827 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1680-1979 of human SMMHC/SMMHC/MYH11 (NP_001035203.1). |
Sequence: | ATAK ENEK KAKS LEAD LMQL QEDL AAAE RARK QADL EKEE LAEE LASS LSGR NALQ DEKR RLEA RIAQ LEEE LEEE QGNM EAMS DRVR KATQ QAEQ LSNE LATE RSTA QKNE SARQ QLER QNKE LRSK LHEM EGAV KSKF KSTI AALE AKIA QLEE QVEQ EARE KQAA TKSL KQKD KKLK EILL QVED ERKM AEQY KEQA EKGN ARVK QLKR QLEE AEEE SQRI NANR RKLQ RELD EATE SNEA MGRE VNAL KSKL RRGN ETSF VPSR RSGG RRVI ENAD GSEE ETDT RDAD FNGT KASE |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IF/ICC,1:50 - 1:200 |
Synonyms: | AAT4; FAA4; SMHC; SMMHC; VSCM2; SMMS-1; SMMHC/MYH11 |
Positive Sample: | Mouse uterus,Rat stomach |
Conjugate: | Unconjugated |
Cellular Localization: | Melanosome. |
Calculated MW: | 227kDa |
Observed MW: | 250kDa |
The protein encoded by this gene is a smooth muscle myosin belonging to the myosin heavy chain family. The gene product is a subunit of a hexameric protein that consists of two heavy chain subunits and two pairs of non-identical light chain subunits. It functions as a major contractile protein, converting chemical energy into mechanical energy through the hydrolysis of ATP. A chromosomal rearrangement involving this gene is associated with acute myeloid leukemia of the M4Eo subtype. Mutations in this gene are associated with visceral myopathy, megacystis-microcolon-intestinal hypoperistalsis syndrome 2, and familial thoracic aortic aneurysm 4.
Purification Method: | Affinity purification |
Gene ID: | 4629 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |