The Myosin 10 Polyclonal Antibody (CAB12029) is a valuable tool for researchers studying myosin 10, a motor protein involved in cell motility and intracellular transport. This antibody, produced in rabbits, exhibits high reactivity specifically with human samples and has been validated for Western blot applications. By binding to the myosin 10 protein, this antibody enables precise detection and analysis in various cell types, making it an essential component for studies in cell biology and cancer research.Myosin 10, also known as Myo10, plays a crucial role in cellular processes such as cell migration, adhesion, and shape changes.
Its involvement in these fundamental functions highlights its importance in physiological and pathological conditions, including cancer metastasis and developmental disorders. By understanding the mechanisms of myosin 10 activity, researchers can gain insights into potential therapeutic targets for diseases related to cell motility and transport. The Myosin 10 Polyclonal Antibody is a valuable tool for exploring the functions and roles of myosin 10 in various cellular contexts.
Product Name:
MYH10 Rabbit Polyclonal Antibody
SKU:
CAB12029
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1908-2007 of human MYH10 (NP_001242941.1).
Sequence:
ARMK QLKR QLEE AEEE ATRA NASR RKLQ RELD DATE ANEG LSRE VSTL KNRL RRGG PISF SSSR SGRR QLHL EGAS LELS DDDT ESKT SDVN ETQP PQSE
This gene encodes a member of the myosin superfamily. The protein represents a conventional non-muscle myosin; it should not be confused with the unconventional myosin-10 (MYO10). Myosins are actin-dependent motor proteins with diverse functions including regulation of cytokinesis, cell motility, and cell polarity. Mutations in this gene have been associated with May-Hegglin anomaly and developmental defects in brain and heart. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
4628
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MYH10 Rabbit pAb (CAB12029) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
