The Myoglobin Polyclonal Antibody (CAB5471) is a valuable tool for researchers studying myoglobin, a protein found in muscle tissue that plays a key role in oxygen transport and storage. This antibody, produced in rabbits, is highly specific to human myoglobin and is optimized for use in Western blot applications. By binding to the myoglobin protein, this antibody allows for precise detection and analysis in a variety of cell types, making it an ideal choice for studies in muscle physiology, cardiovascular health, and exercise science.Myoglobin is essential for muscle function, as it helps facilitate the delivery of oxygen to muscle cells during periods of increased activity.
Abnormal levels of myoglobin can indicate muscle damage or disease, making it a valuable biomarker for conditions such as heart attacks, rhabdomyolysis, and muscular dystrophy. By accurately measuring myoglobin levels with the CAB5471 antibody, researchers can gain valuable insights into the physiological and pathological processes affecting muscle tissue.Overall, the Myoglobin Polyclonal Antibody (CAB5471) is a reliable tool for investigating the role of myoglobin in health and disease. Its high specificity and sensitivity make it a valuable asset for researchers seeking to understand the intricate mechanisms underlying muscle function and related disorders.
Product Name:
Myoglobin Rabbit Polyclonal Antibody
SKU:
CAB5471
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-154 of human Myoglobin (NP_005359.1).
This gene encodes a member of the globin superfamily and is predominantly expressed in skeletal and cardiac muscles. The encoded protein forms a monomeric globular haemoprotein that is primarily responsible for the storage and facilitated transfer of oxygen from the cell membrane to the mitochondria. This protein also plays a role in regulating physiological levels of nitric oxide. Multiple transcript variants encoding distinct isoforms exist for this gene.
Purification Method:
Affinity purification
Gene ID:
4151
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using Myoglobin Rabbit pAb (CAB5471) at 1:1000 dilution.Secondary antibody:HRP Goat Anti-Rabbit IgG (H+L)(CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection:ECL Basic Kit (AbGn00020).Negative control (NC): Rat liver.Exposuretime: 1s.
