MYOF Rabbit Polyclonal Antibody (CAB15427)
- SKU:
- CAB15427
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | MYOF Rabbit Polyclonal Antibody |
SKU: | CAB15427 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human MYOF (NP_038479.1). |
Sequence: | MLRV IVES ASNI PKTK FGKP DPIV SVIF KDEK KKTK KVDN ELNP VWNE ILEF DLRG IPLD FSSS LGII VKDF ETIG QNKL IGTA TVAL KDLT GDQS RSLP YKLI SLLN EKGQ DTGA TIDL VIGY DPPS APHP NDLS GPSV PGMG GDGE EDEG DEDR LDNA VRGP GPKG PVGT VSEA QLAR RLTK VKNS RR |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | HAE7; FER1L3; OF |
Positive Sample: | HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasmic vesicle membrane, Nucleus membrane, Single-pass type II membrane protein. |
Calculated MW: | 235kDa |
Observed MW: | 250kDa |
Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Two transcript variants encoding different isoforms have been found for this gene. Other possible variants have been detected, but their full-length nature has not been determined.
Purification Method: | Affinity purification |
Gene ID: | 26509 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |