MYOC Rabbit Polyclonal Antibody (CAB1589)
- SKU:
- CAB1589
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | MYOC Rabbit Polyclonal Antibody |
SKU: | CAB1589 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 245-504 of human MYOC (NP_000252.1). |
Sequence: | CGEL VWVG EPLT LRTA ETIT GKYG VWMR DPKP TYPY TQET TWRI DTVG TDVR QVFE YDLI SQFM QGYP SKVH ILPR PLES TGAV VYSG SLYF QGAE SRTV IRYE LNTE TVKA EKEI PGAG YHGQ FPYS WGGY TDID LAVD EAGL WVIY STDE AKGA IVLS KLNP ENLE LEQT WETN IRKQ SVAN AFII CGTL YTVS SYTS ADAT VNFA YDTG TGIS KTLT IPFK NRYK YSSM IDYN PLEK KLFA WDNL NMVT YDIK LSKM |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | GPOA; JOAG; TIGR; GLC1A; JOAG1; MYOC |
Positive Sample: | Raji,U-937,BT-474,Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell projection, Cytoplasmic vesicle, Endoplasmic reticulum, Golgi apparatus, Mitochondrion, Mitochondrion inner membrane, Mitochondrion intermembrane space, Mitochondrion outer membrane, Rough endoplasmic reticulum, Secreted, cilium, exosome, extracellular matrix, extracellular space. |
Calculated MW: | 57kDa |
Observed MW: | 65kDa |
MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.
Purification Method: | Affinity purification |
Gene ID: | 4653 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |