The Myo7b Polyclonal Antibody (PAC010704) is a valuable tool for researchers studying the Myo7b protein, which plays a crucial role in cellular processes, particularly in the context of hearing and vision. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By targeting the Myo7b protein, researchers can effectively detect and analyze its expression in various cell types, making it well-suited for investigations in molecular biology and neuroscience.Myo7b, also known as Myosin VIIb, is an essential motor protein involved in the transport of cellular cargo and the maintenance of cell structure. Its involvement in sensory functions, such as the development of hair cells in the inner ear and the structure of photoreceptor cells in the retina, underscores its importance in auditory and visual processes.
Research on Myo7b is particularly relevant in the study of sensory perception disorders, including deafness and vision impairments.The Myo7b Polyclonal Antibody serves as a valuable resource for scientists seeking to explore the functions and mechanisms of action of Myo7b, shedding light on its roles in cellular physiology and sensory biology. Its utility in various research applications makes it a versatile tool for investigating the intricate functions of this protein in health and disease.
Myosins are actin-based motor molecules with ATPase activity. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. As part of the intermicrovillar adhesion complex/IMAC plays a role in epithelial brush border differentiation, controlling microvilli organization and length. May link the complex to the actin core bundle of microvilli (Probable).
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene is found in brush border microvilli of epithelial cells in the intestines and kidneys. The encoded protein is involved in linking protocadherins to the actin cytoskeleton and is essential for proper microvilli function. This protein aids in the accumulation of intermicrovillar adhesion components such as harmonin and ANKS4B, and this accumulation is necessary for normal brush border action. [provided by RefSeq, Jan 2017]
