The Myo6 Polyclonal Antibody (CAB13033) is a vital tool for researchers studying the Myosin VI protein, an essential molecular motor involved in various cellular processes such as intracellular trafficking and membrane dynamics. This antibody, produced in rabbits, exhibits strong reactivity towards human samples and has been extensively validated for use in Western blot applications.Myosin VI plays a crucial role in cell migration, endocytosis, and cell adhesion, making it a key player in both normal cellular function and disease pathogenesis. By targeting the Myo6 protein, researchers can gain valuable insights into its function and role in various physiological and pathological processes.
With its high specificity and sensitivity, the Myo6 Polyclonal Antibody is an invaluable tool for researchers in the fields of cell biology, biochemistry, and molecular biology. Its ability to detect and analyze Myosin VI in different cell types offers valuable information for studies on cellular dynamics, signal transduction, and disease mechanisms. This antibody is essential for advancing our understanding of Myosin VI and its implications in health and disease.
Product Name:
MYO6 Rabbit Polyclonal Antibody
SKU:
CAB13033
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1016-1285 of human MYO6 (NP_004990.3).
This gene encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Purification Method:
Affinity purification
Gene ID:
4646
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MYO6 Rabbit pAb (CAB13033) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
