MYO6 Rabbit Polyclonal Antibody (CAB13033)
- SKU:
- CAB13033
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | MYO6 Rabbit Polyclonal Antibody |
SKU: | CAB13033 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1016-1285 of human MYO6 (NP_004990.3). |
Sequence: | IAQS EAEL ISDE AQAD LALR RNDG TRPK MTPE QMAK EMSE FLSR GPAV LATK AAAG TKKY DLSK WKYA ELRD TINT SCDI ELLA ACRE EFHR RLKV YHAW KSKN KKRN TETE QRAP KSVT DYDF APFL NNSP QQNP AAQI PARQ REIE MNRQ QRFF RIPF IRPA DQYK DPQS KKKG WWYA HFDG PWIA RQME LHPD KPPI LLVA GKDD MEMC ELNL EETG LTRK RGAE ILPR QFEE IWER CGGI QYLQ NAIE SRQA RPTY ATAM LQSL LK |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | DFNA22; DFNB37; MYO6 |
Positive Sample: | HT-29,Mouse brain,Mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Cell projection, Cytoplasm, Cytoplasmic vesicle, Golgi apparatus, Membrane, Nucleus, Peripheral membrane protein, Peripheral membrane protein, clathrin-coated pit, clathrin-coated vesicle membrane, perinuclear region, ruffle membrane, trans-Golgi network membrane. |
Calculated MW: | 150kDa |
Observed MW: | 150kDa |
This gene encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Purification Method: | Affinity purification |
Gene ID: | 4646 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |