The Myo5B Polyclonal Antibody (CAB8558) is a valuable tool for researchers studying Myosin Vb (Myo5B), a motor protein involved in intracellular transport and cell motility. This antibody is produced in rabbits and has high reactivity with human samples, making it suitable for use in Western blot applications. By binding to the Myo5B protein, this antibody allows for the detection and analysis of Myo5B in various cell types, making it an ideal choice for studies in cell biology and cancer research.Myosin Vb plays a crucial role in maintaining cell polarity, transporting vesicles along actin filaments, and regulating membrane trafficking.
Dysregulation of Myo5B has been implicated in various diseases, including cancer and neurological disorders. By studying Myo5B using this antibody, researchers can gain a better understanding of its function and its potential role in disease pathology. This antibody is a valuable tool for investigating the molecular mechanisms underlying cellular processes and may lead to the development of targeted therapies for Myo5B-related conditions.
Product Name:
MYO5B Rabbit Polyclonal Antibody
SKU:
CAB8558
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1440-1690 of human MYO5B (NP_001073936.1).
The protein encoded by this gene, together with other proteins, may be involved in plasma membrane recycling. Mutations in this gene are associated with microvillous inclusion disease.
Purification Method:
Affinity purification
Gene ID:
4645
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MYO5B antibody (CAB8558) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.
