MYO5A Rabbit Polyclonal Antibody (CAB9830)
- SKU:
- CAB9830
- Product Type:
- Antibody
- Applications:
- WB
- IHC
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | MYO5A Rabbit Polyclonal Antibody |
SKU: | CAB9830 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 950-1150 of human MYO5A (NP_000250.3). |
Sequence: | LTNL EGIY NSET EKLR SDLE RLQL SEEE AKVA TGRV LSLQ EEIA KLRK DLEQ TRSE KKCI EEHA DRYK QETE QLVS NLKE ENTL LKQE KEAL NHRI VQQA KEMT ETME KKLV EETK QLEL DLND ERLR YQNL LNEF SRLE ERYD DLKE EMTL MVHV PKPG HKRT DSTH SSNE SEYI FSSE IAEM EDIP SRTE EPSE KKVP L |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | GS1; MYO5; MYH12; MYR12; MYO5A |
Positive Sample: | HeLa,Jurkat,MCF7,HT-1080,Mouse spleen,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | actin cytoskeleton, cytoplasm, cytosol, extracellular exosome, filopodium tip, melanosome |
Calculated MW: | 215kDa |
Observed MW: | 240kDa |
This gene is one of three myosin V heavy-chain genes, belonging to the myosin gene superfamily. Myosin V is a class of actin-based motor proteins involved in cytoplasmic vesicle transport and anchorage, spindle-pole alignment and mRNA translocation. The protein encoded by this gene is abundant in melanocytes and nerve cells. Mutations in this gene cause Griscelli syndrome type-1 (GS1), Griscelli syndrome type-3 (GS3) and neuroectodermal melanolysosomal disease, or Elejalde disease. Multiple alternatively spliced transcript variants encoding different isoforms have been reported, but the full-length nature of some variants has not been determined.
Purification Method: | Affinity purification |
Gene ID: | 4644 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |