The Myo5a Polyclonal Antibody (CAB9830) is a valuable tool for researchers studying Myo5a, a motor protein involved in intracellular transport and cell migration. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for use in various research applications such as Western blot and immunofluorescence.Myo5a plays a crucial role in facilitating the movement of vesicles and organelles within cells, making it essential for cellular processes such as protein trafficking and cell division. Dysregulation of Myo5a has been implicated in various diseases, including cancer and neurological disorders, highlighting the importance of studying its function and regulation.
By using the Myo5a Polyclonal Antibody, researchers can confidently detect and analyze Myo5a protein levels in different cell types and tissue samples, providing valuable insights into its role in cellular physiology and disease pathogenesis. This antibody is a valuable tool for furthering our understanding of Myo5a and its potential as a therapeutic target for various diseases.
Product Name:
MYO5A Rabbit Polyclonal Antibody
SKU:
CAB9830
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 950-1150 of human MYO5A (NP_000250.3).
This gene is one of three myosin V heavy-chain genes, belonging to the myosin gene superfamily. Myosin V is a class of actin-based motor proteins involved in cytoplasmic vesicle transport and anchorage, spindle-pole alignment and mRNA translocation. The protein encoded by this gene is abundant in melanocytes and nerve cells. Mutations in this gene cause Griscelli syndrome type-1 (GS1), Griscelli syndrome type-3 (GS3) and neuroectodermal melanolysosomal disease, or Elejalde disease. Multiple alternatively spliced transcript variants encoding different isoforms have been reported, but the full-length nature of some variants has not been determined.
Purification Method:
Affinity purification
Gene ID:
4644
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MYO5A antibody (CAB9830) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
