The MYO1C Polyclonal Antibody (CAB6936) is specifically designed for research involving MYO1C, a protein that plays a role in various cellular processes such as cell motility, membrane trafficking, and signal transduction. This antibody, generated in rabbits, is highly sensitive and reactive with human samples, making it an ideal tool for studies in cell biology and cancer research.MYO1C, a member of the myosin superfamily of actin-based molecular motors, is involved in the movement and positioning of cellular membranes and organelles. Its dysregulation has been implicated in cancer progression and metastasis, making it a potential target for therapeutic interventions.
By using the MYO1C Polyclonal Antibody, researchers can detect and analyze MYO1C expression in a variety of cell types, furthering the understanding of its function in normal and disease states.Overall, the MYO1C Polyclonal Antibody is a valuable tool for scientists investigating the role of MYO1C in cellular processes, cancer biology, and potential therapeutic strategies. Its high specificity and versatility in applications such as Western blotting make it a reliable choice for advancing research in these areas.
Product Name:
MYO1C Rabbit Polyclonal Antibody
SKU:
CAB6936
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 769-1028 of human MYO1C (NP_203693.3).
This gene encodes a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene. The related gene myosin IE has been referred to as myosin IC in the literature, but it is a distinct locus on chromosome 19.
Purification Method:
Affinity purification
Gene ID:
4641
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using MYO1C Rabbit pAb (CAB6936) at 1:1500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
