MYO1C Rabbit Polyclonal Antibody (CAB6936)
- SKU:
- CAB6936
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | MYO1C Rabbit Polyclonal Antibody |
SKU: | CAB6936 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 769-1028 of human MYO1C (NP_203693.3). |
Sequence: | ENAF FLDH VRTS FLLN LRRQ LPQN VLDT SWPT PPPA LREA SELL RELC IKNM VWKY CRSI SPEW KQQL QQKA VASE IFKG KKDN YPQS VPRL FIST RLGT DEIS PRVL QALG SEPI QYAV PVVK YDRK GYKP RSRQ LLLT PNAV VIVE DAKV KQRI DYAN LTGI SVSS LSDS LFVL HVQR ADNK QKGD VVLQ SDHV IETL TKTA LSAN RVNS ININ QGSI TFAG GPGR DGTI DFTP GSEL LITK AKNG HLAV VAPR LNSR |
Tested Applications: | WB IHC-P IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | NMI; MMIb; myr2; MyoIC; MMI-beta; MYO1C |
Positive Sample: | A-549,HL-60(Negative control),Mouse lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cell projection, Cytoplasm, Cytoplasmic side, Cytoplasmic vesicle, Nucleus, Nucleus, Peripheral membrane protein, nuclear pore complex, nucleolus, nucleoplasm, ruffle, stereocilium membrane. |
Calculated MW: | 122kDa |
Observed MW: | 122kDa |
This gene encodes a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene. The related gene myosin IE has been referred to as myosin IC in the literature, but it is a distinct locus on chromosome 19.
Purification Method: | Affinity purification |
Gene ID: | 4641 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |