The Myo16 Polyclonal Antibody (PACO03678) is a valuable tool for researchers studying the Myo16 protein, which is involved in various cellular processes related to muscle function and development. Raised in rabbits, this antibody exhibits high reactivity with human samples and has been validated for use in Western blot applications.Myo16, also known as myosin XVI, is a member of the myosin superfamily of motor proteins and is expressed in various tissues, including skeletal muscle and heart. Its role in muscle cell development and function makes it a key target for research in the fields of muscle biology, myopathies, and muscle-related diseases.
By specifically binding to the Myo16 protein, this antibody allows for the detection and analysis of Myo16 in different cell types, providing valuable insights into its functions and signaling pathways. Researchers in the fields of muscle biology, neurology, and molecular biology will find this antibody essential for their studies on Myo16 and its implications in various physiological and pathological conditions.
Antibody Name:
MYO16 Antibody
Antibody SKU:
PACO03678
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human Myosin XVI.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
MYO16: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. May be involved in targeting of the catalytic subunit of protein phosphatase 1 during brain development. Activates PI3K and concomitantly recruits the WAVE1 complex to the close vicinity of PI3K and regulates neuronal morphogenesis. Belongs to the NYAP family. 4 isoforms of the human protein are produced by alternative splicing.Protein type: Contractile; Motor; Cell cycle regulation; Actin-bindingChromosomal Location of Human Ortholog: 13q33.3Cellular Component: cytoplasm; myosin complex; nucleoplasm; perinuclear region of cytoplasm; plasma membraneMolecular Function: actin filament binding; ATP binding; motor activityBiological Process: cerebellum development; metabolic process; negative regulation of cell proliferation
