The MYO10 Polyclonal Antibody (CAB12471) is a valuable tool for researchers studying MYO10, a motor protein that plays a crucial role in cell migration and intracellular transport. This antibody, produced in rabbits, is highly specific to MYO10 in human samples and is validated for use in Western blot and immunofluorescence applications.MYO10 is a unique myosin that is involved in the movement of organelles and vesicles along actin filaments within cells. Its abnormalities have been linked to various diseases, including cancer and neurodevelopmental disorders. By targeting MYO10 with this antibody, researchers can investigate its role in cellular processes and disease pathogenesis with high specificity and sensitivity.
The MYO10 Polyclonal Antibody is an essential tool for scientists studying cell biology, cancer biology, and neurobiology. Its ability to detect and analyze MYO10 protein expression in various cell types makes it versatile for a wide range of research applications. By understanding the function of MYO10, researchers can gain insights into disease mechanisms and potentially develop targeted therapies in the future.
Product Name:
MYO10 Rabbit Polyclonal Antibody
SKU:
CAB12471
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 845-944 of human MYO10 (NP_036466.2).
This gene encodes a member of the myosin superfamily. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-10 (MYH10). Unconventional myosins contain the basic domains of conventional myosins and are further distinguished from class members by their tail domains. This gene functions as an actin-based molecular motor and plays a role in integration of F-actin and microtubule cytoskeletons during meiosis.
Purification Method:
Affinity purification
Gene ID:
4651
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MYO10 antibody (CAB12471) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 20s.
