The Mylip Polyclonal Antibody (CAB6166) is a valuable tool for researchers studying Mylip, a key regulator of lipid metabolism and cholesterol homeostasis. This antibody, generated in rabbits, is highly specific for Mylip and is validated for use in various applications, including Western blotting. By binding to the Mylip protein, this antibody allows for the detection and analysis of Mylip expression in different cell types, making it ideal for studies in metabolism, cardiovascular health, and related fields.
Mylip, also known as E3 ubiquitin ligase, plays a crucial role in the degradation of lipid-modifying enzymes, thereby impacting lipid levels and overall metabolism. Dysregulation of Mylip has been implicated in various metabolic disorders, making it a potential target for therapeutic interventions aimed at restoring lipid homeostasis. Research into the function and regulation of Mylip is essential for developing strategies to combat conditions such as obesity, dyslipidemia, and heart disease.
Product Name:
MYLIP Rabbit Polyclonal Antibody
SKU:
CAB6166
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 266-445 of human MYLIP (NP_037394.2).
The ERM protein family members ezrin, radixin, and moesin are cytoskeletal effector proteins linking actin to membrane-bound proteins at the cell surface. Myosin regulatory light chain interacting protein (MYLIP) is a novel ERM-like protein that interacts with myosin regulatory light chain and inhibits neurite outgrowth.
Purification Method:
Affinity purification
Gene ID:
29116
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using MYLIP Rabbit pAb (CAB6166) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
