MYL9/MYL12A Antibody (PACO01087)
- SKU:
- PACO01087
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
MYL9/MYL12A Antibody (PACO01087)
The MYL9-MYL12A Antibody (PACO01087) is a high-quality polyclonal antibody designed for research involving MYL9 and MYL12A proteins. These proteins are essential components of the myosin II complex, playing a critical role in cell motility and contractility. The antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications.The MYL9-MYL12A Antibody binds specifically to the MYL9 and MYL12A proteins, enabling precise detection and analysis in various cell types. This makes it an ideal tool for researchers studying cell biology, muscle contraction, and cytoskeletal dynamics.
Understanding the function and regulation of MYL9 and MYL12A is crucial for advancing our knowledge of cellular processes and developing potential therapies for conditions related to abnormal cell motility.Overall, the MYL9-MYL12A Antibody (PACO01087) offers a reliable and effective solution for studies focusing on the MYL9 and MYL12A proteins, providing valuable insights into their roles in cellular physiology and potential implications for various diseases and disorders.
| Antibody Name: | MYL9/MYL12A Antibody |
| Antibody SKU: | PACO01087 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | synthesized peptide derived from human MRLC2 around the non-phosphorylation site of S18. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | MYL9; MLC2; MRLC1; MYRL2; Myosin regulatory light polypeptide 9; 20 kDa myosin light chain; LC20; MLC-2C; Myosin RLC; Myosin regulatory light chain 2; smooth muscle isoform; Myosin regulatory light chain 9; Myosin regulatory light chain MRL |
| UniProt Protein Function: | MRLC1: Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion. Myosin is an hexamer of 2 heavy chains and 4 light chains. Smooth muscle tissues and in some, but not all, nonmuscle cells. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Contractile; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 20q11.23 Cellular Component: cytosol; muscle myosin complex; stress fiber; Z disc Molecular Function:calcium ion binding; myosin heavy chain binding; structural constituent of muscle Biological Process: axon guidance; ephrin receptor signaling pathway; muscle contraction; regulation of muscle contraction; small GTPase mediated signal transduction |
| NCBI Summary: | Myosin, a structural component of muscle, consists of two heavy chains and four light chains. The protein encoded by this gene is a myosin light chain that may regulate muscle contraction by modulating the ATPase activity of myosin heads. The encoded protein binds calcium and is activated by myosin light chain kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P24844 |
| NCBI GenInfo Identifier: | 20141521 |
| NCBI Gene ID: | 10398 |
| NCBI Accession: | P24844.4 |
| UniProt Secondary Accession: | P24844,Q9BQL9, Q9BUF9, Q9H136, E1P5T6, |
| UniProt Related Accession: | P24844 |
| Molecular Weight: | 13,866 Da |
| NCBI Full Name: | Myosin regulatory light polypeptide 9 |
| NCBI Synonym Full Names: | myosin light chain 9 |
| NCBI Official Symbol: | MYL9Â Â |
| NCBI Official Synonym Symbols: | LC20; MLC2; MRLC1; MYRL2; MLC-2CÂ Â |
| NCBI Protein Information: | myosin regulatory light polypeptide 9 |
| UniProt Protein Name: | Myosin regulatory light polypeptide 9 |
| UniProt Synonym Protein Names: | 20 kDa myosin light chain; LC20; MLC-2C; Myosin RLC; Myosin regulatory light chain 2, smooth muscle isoform; Myosin regulatory light chain 9; Myosin regulatory light chain MRLC1 |
| Protein Family: | Myosin regulatory light polypeptide |
| UniProt Gene Name: | MYL9Â Â |
| UniProt Entry Name: | MYL9_HUMAN |
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