The MYL3 Polyclonal Antibody (CAB6662) is a valuable tool for researchers studying MYL3, a critical protein involved in muscle contraction and cardiac function. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. It binds specifically to the MYL3 protein, allowing for accurate detection and analysis in a variety of cell types, making it ideal for studies in cardiology and muscle biology.MYL3, also known as myosin light chain 3, is essential for proper muscle function and is particularly important in the heart.
Mutations in the MYL3 gene have been linked to various cardiac conditions, making it a key target for research in cardiovascular disease. By studying the expression and function of MYL3, researchers can gain valuable insights into the mechanisms underlying heart muscle function and dysfunction, with potential implications for the development of novel therapeutics.
Product Name:
MYL3 Rabbit Polyclonal Antibody
SKU:
CAB6662
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-195 of human MYL3 (NP_000249.1).
MYL3 encodes myosin light chain 3, an alkali light chain also referred to in the literature as both the ventricular isoform and the slow skeletal muscle isoform. Mutations in MYL3 have been identified as a cause of mid-left ventricular chamber type hypertrophic cardiomyopathy.
Purification Method:
Affinity purification
Gene ID:
4634
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MYL3 antibody (CAB6662) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
