The MYL2 Polyclonal Antibody (CAB14188) is a valuable tool for researchers studying the MYL2 gene, which encodes the myosin light chain 2 protein involved in muscle contraction. This antibody, generated in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications. By binding to the MYL2 protein, researchers can effectively detect and analyze the expression of MYL2 in various cell types.MYL2 is a critical component of the contractile apparatus in muscle cells and plays a key role in muscle function. Mutations in the MYL2 gene have been associated with various cardiac conditions, making it a target of interest in cardiovascular research.
Additionally, MYL2 has been implicated in skeletal muscle disorders and could be a potential target for therapeutic interventions.By using the MYL2 Polyclonal Antibody, researchers can further their understanding of the role of MYL2 in muscle physiology and pathophysiology, ultimately leading to advancements in the diagnosis and treatment of muscle-related disorders. This antibody is a valuable tool for studies in cardiology, neurology, and muscle biology.
Product Name:
MYL2 Rabbit Polyclonal Antibody
SKU:
CAB14188
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-166 of human MYL2 (NP_000423.2).
This gene encodes a major sarcomeric protein in mammalian striated muscle. The encoded protein plays a role in embryonic heart muscle structure and function, while phosphorylation of the encoded protein is involved in cardiac myosin cycling kinetics, torsion and function in adults. Mutations in this gene are associated with hypertrophic cardiomyopathy 10 and infant-onset myopathy.
Purification Method:
Affinity purification
Gene ID:
4633
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MYL2 antibody (CAB14188) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
