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MYL2 Monoclonal Antibody [PAT3B2AT] (CPAB0543)

SKU:
CPAB0543
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG2b
Clone:
PAT3B2AT
Applications:
WB
ELISA
€149
Frequently bought together:

Description

system_update_alt Datasheet

MYL2 Monoclonal Antibody [PAT3B2AT] (CPAB0543)

The MYL2 Polyclonal Antibody (CPAB0543) is a valuable tool for researchers studying MYL2, a crucial protein involved in muscle contraction and heart function. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically targeting the MYL2 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential asset for studies in cardiovascular biology and muscle physiology.MYL2, also known as myosin light chain 2, is a key component of the sarcomere, the basic unit of muscle contraction. Its role in regulating muscle contraction and relaxation makes it a vital player in cardiac function and overall muscle performance.

Research into MYL2 is critical for understanding the mechanisms underlying cardiovascular diseases, such as cardiomyopathies and heart failure, as well as skeletal muscle disorders.By utilizing the MYL2 Polyclonal Antibody, researchers can delve deeper into the molecular pathways involving MYL2 and its interactions with other proteins in various cellular contexts. This antibody is a valuable tool for investigating the role of MYL2 in health and disease, paving the way for potential therapeutic strategies targeting MYL2-related conditions.

Product Name:MYL2 Antibody
Product Sku:CPAB0543
Size:5μg
Host Species:Mouse
Immunogen:Anti-human MYL2 mAb is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human MYL2 amino acids 1-166 purified from Ecoli.
Clone:PAT3B2AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:MYL2 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG2b
Background:MYL2 regulatory light chain is associated with cardiac myosin beta (or slow) heavy chain. Ca+ activates the phosphorylation of regulatory light chain that in turn activates contraction. Mutations in this MYL2 gene are related with mid-left ventricular chamber type hypertrophic cardiomyopathy. MYL2 is an essential protein that plays a role in the regulation of myosin ATPase activity in smooth muscle. MYL2 phosphorylation is regulated by ROCK and MLC kinase and is involved in platelet biogenesis by controlling proplatelet formation and fragmentation.
Synonyms:MLC2, CMH10, MYL-2, Myosin regulatory light chain 2, MYOSIN LIGHT CHAIN REGULATORY VENTRICULAR, DKFZp779C0562, MYL2, MLC-2v, MLC-2.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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