MYH7/β-MHC Monoclonal Antibody (CAB22140)
- SKU:
- CAB22140
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
Product Name: | MYH7/β-MHC Monoclonal Antibody |
SKU: | CAB22140 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1700-1800 of human MYH7/β-MHC (NP_000248.2). |
Sequence: | KLAE QELI ETSE RVQL LHSQ NTSL INQK KKMD ADLS QLQT EVEE AVQE CRNA EEKA KKAI TDAA MMAE ELKK EQDT SAHL ERMK KNME QTIK DLQH RLDE A |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 |
Synonyms: | CMH1; MPD1; SPMD; SPMM; CMD1S; MYHCB; CMYP7A; CMYP7B; MYH7/β-MHC |
Positive Sample: | Mouse heart,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | myofibril, sarcomere, Cytoplasm |
Calculated MW: | 223kDa |
Observed MW: | 220-230kDa |
Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing distal myopathy.
Purification Method: | Affinity purification |
Gene ID: | 4625 |
Clone Number: | ARC55749 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |