The MYH6 Polyclonal Antibody (CAB12964) is a valuable tool for research involving MYH6, a myosin heavy chain protein that is essential for cardiac muscle contraction. This antibody, produced in rabbits, is highly specific to human MYH6 samples and is validated for use in multiple applications, including Western blotting. It binds specifically to the MYH6 protein, allowing for precise detection and analysis in various cell types, making it ideal for studies in cardiology and cardiovascular research.MYH6 is a critical component of the cardiac muscle sarcomere and plays a key role in heart function.
Mutations in the MYH6 gene have been linked to various cardiac disorders, making it an important target for research into cardiovascular diseases. Understanding the function and expression of MYH6 is crucial for developing potential therapies for heart conditions and improving overall cardiovascular health.Overall, the MYH6 Polyclonal Antibody (CAB12964) is a reliable tool for researchers studying MYH6 and its role in cardiac muscle physiology and pathology. It offers high specificity and sensitivity, making it an essential reagent for advancing our understanding of heart function and disease.
Product Name:
MYH6/α-MHC Rabbit Polyclonal Antibody
SKU:
CAB12964
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human MYH6/α-MHC (NP_002462.2).
Cardiac muscle myosin is a hexamer consisting of two heavy chain subunits, two light chain subunits, and two regulatory subunits. This gene encodes the alpha heavy chain subunit of cardiac myosin. The gene is located approximately 4kb downstream of the gene encoding the beta heavy chain subunit of cardiac myosin. Mutations in this gene cause familial hypertrophic cardiomyopathy and atrial septal defect 3.
Purification Method:
Affinity purification
Gene ID:
4624
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MYH6/α-MHC Rabbit pAb (CAB12964) at 1:700 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s.
