SMMHC/MYH11 Rabbit Monoclonal Antibody (CAB4064)
- SKU:
- CAB4064
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | SMMHC/MYH11 Rabbit Monoclonal Antibody |
SKU: | CAB4064 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1160-1313 of human SMMHC/MYH11 (NP_002465.1). |
Sequence: | DSTA TQQE LRAK REQE VTVL KKAL DEET RSHE AQVQ EMRQ KHAQ AVEE LTEQ LEQF KRAK ANLD KNKQ TLEK ENAD LAGE LRVL GQAK QEVE HKKK KLEA QVQE LQSK CSDG ERAR AELN DKVH KLQN EVES VTGM LNEA EGKA IKLA KDVA SL |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:2000 - 1:10000 IF/ICC,1:500 - 1:1000 |
Synonyms: | AAT4; FAA4; SMHC; SMMHC; VSCM2; SMMS-1; SMMHC/MYH11 |
Positive Sample: | Mouse lung,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Melanosome |
Calculated MW: | 227kDa |
Observed MW: | 250kDa |
The protein encoded by this gene is a smooth muscle myosin belonging to the myosin heavy chain family. The gene product is a subunit of a hexameric protein that consists of two heavy chain subunits and two pairs of non-identical light chain subunits. It functions as a major contractile protein, converting chemical energy into mechanical energy through the hydrolysis of ATP. A chromosomal rearrangement involving this gene is associated with acute myeloid leukemia of the M4Eo subtype. Mutations in this gene are associated with visceral myopathy, megacystis-microcolon-intestinal hypoperistalsis syndrome 2, and familial thoracic aortic aneurysm 4.
Purification Method: | Affinity purification |
Gene ID: | 4629 |
Clone Number: | ARC51911 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |