null

MYH1/MYH2/MYH3/MYH4/MYH6/MYH7/MYH8 Antibody (PACO02108)

SKU:
PACO02108
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€319

Description

system_update_altDatasheetsystem_update_altMSDS

MYH1/MYH2/MYH3/MYH4/MYH6/MYH7/MYH8 Antibody (PACO02108)

The MYH1-MYH8 Polyclonal Antibody (PACO02108) is a cutting-edge tool for researchers studying myosin proteins, specifically MYH1, MYH2, MYH3, MYH4, MYH6, MYH7, and MYH8. These myosin proteins are essential for muscle contraction and function, making them key targets for investigations in muscle biology, physiology, and disease.This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the various MYH proteins, researchers can accurately detect and quantify their expression levels in different cell types and tissues. This versatility makes the MYH1-MYH8 Polyclonal Antibody an invaluable tool for a wide range of studies, from understanding muscle development to exploring the role of myosins in diseases such as muscular dystrophy and cardiac disorders.

With its high specificity and sensitivity, the MYH1-MYH8 Polyclonal Antibody opens up new possibilities for unraveling the intricate functions of myosin proteins and their implications in various physiological and pathological processes. Researchers can rely on this antibody to drive forward their investigations and gain valuable insights into the complex world of muscle biology.

Antibody Name:MYH1/MYH2/MYH3/MYH4/MYH6/MYH7/MYH8 Antibody
Antibody SKU:PACO02108
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, WB
Recommended Dilutions:WB:1:500-1:2000
Species Reactivity:Human, Mouse, Rat
Immunogen:synthesized peptide derived from human MYH-pan around the non-acetylation site of K1394.
Form:Liquid
Storage Buffer:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:MYH1; Myosin-1; Myosin heavy chain 1; Myosin heavy chain 2x; MyHC-2x; Myosin heavy chain IIx/d; MyHC-IIx/d; Myosin heavy chain, skeletal muscle, adult 1; MYH2; MYHSA2; Myosin-2; Myosin heavy chain 2
UniProt Protein Function:MYH1: Muscle contraction.
UniProt Protein Details:

Protein type:Motility/polarity/chemotaxis; Motor

Chromosomal Location of Human Ortholog: 17p13.1

Cellular Component: muscle myosin complex; A band

Molecular Function:calmodulin binding; motor activity; actin binding; ATP binding

Biological Process: muscle contraction; metabolic process

NCBI Summary:Myosin is a major contractile protein which converts chemical energy into mechanical energy through the hydrolysis of ATP. Myosin is a hexameric protein composed of a pair of myosin heavy chains (MYH) and two pairs of nonidentical light chains. Myosin heavy chains are encoded by a multigene family. In mammals at least 10 different myosin heavy chain (MYH) isoforms have been described from striated, smooth, and nonmuscle cells. These isoforms show expression that is spatially and temporally regulated during development. [provided by RefSeq, Jul 2008]
UniProt Code:P12882
NCBI GenInfo Identifier:226694176
NCBI Gene ID:4619
NCBI Accession:P12882.3
UniProt Secondary Accession:P12882,Q14CA4, Q9Y622,
UniProt Related Accession:P12882
Molecular Weight:Calculated MW: 223kDaObserved MW: 260kDa
NCBI Full Name:Myosin-1
NCBI Synonym Full Names:myosin, heavy chain 1, skeletal muscle, adult
NCBI Official Symbol:MYH1  
NCBI Official Synonym Symbols:MYHa; HEL71; MYHSA1; MyHC-2x; MyHC-2X/D  
NCBI Protein Information:myosin-1; myHC-IIx/d; myosin heavy chain 1; myosin heavy chain 2x; myosin heavy chain IIx/d; epididymis luminal protein 71; myosin heavy chain, skeletal muscle, adult 1; myosin, heavy polypeptide 1, skeletal muscle, adult
UniProt Protein Name:Myosin-1
UniProt Synonym Protein Names:Myosin heavy chain 1; Myosin heavy chain 2x; MyHC-2x; Myosin heavy chain IIx/d; MyHC-IIx/d; Myosin heavy chain, skeletal muscle, adult 1
UniProt Gene Name:MYH1  
UniProt Entry Name:MYH1_HUMAN

Related Products