The Myelin Oligodendrocyte Glycoprotein Rabbit Monoclonal Antibody (CAB3992) is a specialized tool for researchers studying the myelin oligodendrocyte glycoprotein (MOG), a key protein involved in the central nervous system function. This antibody, developed using rabbit monoclonal technology, exhibits high specificity and sensitivity for detecting MOG in human samples.MOG is essential for maintaining the structure and function of myelin, the protective sheath surrounding nerve fibers. Dysregulation of MOG has been implicated in various neurological disorders, including multiple sclerosis. By targeting MOG, researchers can gain valuable insights into the pathophysiology of these conditions and potentially identify novel therapeutic approaches.
Validated for use in Western blot applications, the Myelin Oligodendrocyte Glycoprotein Rabbit Monoclonal Antibody (CAB3992) enables precise detection and quantification of MOG in various cell types. Its reliability and accuracy make it a valuable asset for studies in neurology, immunology, and neurodegenerative diseases.With its ability to specifically bind to MOG, this antibody facilitates the investigation of MOG-related mechanisms and pathways, offering a deeper understanding of the role of this protein in health and disease. Researchers can leverage the Myelin Oligodendrocyte Glycoprotein Rabbit Monoclonal Antibody (CAB3992) to advance their research and contribute to the development of
Cell membrane, Multi-pass membrane protein, Single-pass type I membrane protein.
Calculated MW:
28kDa
Observed MW:
28kDa
The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified.
Purification Method:
Affinity purification
Gene ID:
4340
Clone Number:
ARC0879
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using Myelin oligodendrocyte glycoprotein Rabbit mAb (CAB3992) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
