MyD88 Rabbit Polyclonal Antibody (CAB16889)
- SKU:
- CAB16889
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | MyD88 Rabbit Polyclonal Antibody |
SKU: | CAB16889 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human MyD88 (NP_002459.2). |
Sequence: | LNVR TQVA ADWT ALAE EMDF EYLE IRQL ETQA DPTG RLLD AWQG RPGA SVGR LLEL LTKL GRDD VLLE LGPS IEED CQKY ILKQ QQEE AEKP LQVA AVDS S |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | WM1; IMD68; MYD88D; MyD88 |
Positive Sample: | Mouse spleen,Rat spleen |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 33kDa |
Observed MW: | 33kDa |
This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 4615 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |