MyD88 Rabbit Polyclonal Antibody (CAB0786)
- SKU:
- CAB0786
- Product Type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | MyD88 Rabbit Polyclonal Antibody |
SKU: | CAB0786 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 60-309 of human MyD88 (NP_002459.2). |
Sequence: | WTAL AEEM DFEY LEIR QLET QADP TGRL LDAW QGRP GASV GRLL ELLT KLGR DDVL LELG PSIE EDCQ KYIL KQQQ EEAE KPLQ VAAV DSSV PRTA ELAG ITTL DDPL GHMP ERFD AFIC YCPS DIQF VQEM IRQL EQTN YRLK LCVS DRDV LPGT CVWS IASE LIEK RCRR MVVV VSDD YLQS KECD FQTK FALS LSPG AHQK RLIP IKYK AMKK EFPS ILRF ITVC DYTN PCTK SWFW TRLA KALS LP |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | WM1; IMD68; MYD88D; MyD88 |
Positive Sample: | A-549,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 33kDa |
Observed MW: | 33kDa |
This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 4615 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |