The MyD88 Monoclonal Antibody is a cutting-edge research tool designed for studying MyD88, a key signaling protein in the innate immune response. This antibody is produced using state-of-the-art monoclonal antibody technology, ensuring high specificity and sensitivity in detection assays.MyD88 is a crucial adaptor protein involved in Toll-like receptor (TLR) and interleukin-1 receptor (IL-1R) signaling pathways, playing a pivotal role in activating pro-inflammatory responses against pathogens. Dysregulation of MyD88 signaling has been linked to various inflammatory diseases, autoimmune disorders, and cancer.This monoclonal antibody has been rigorously validated for use in various applications, including Western blotting, immunofluorescence, and immunoprecipitation.
Its high reactivity with human samples makes it an excellent choice for researchers studying immune responses, inflammation, and infectious diseases.By targeting MyD88, researchers can gain valuable insights into the intricate mechanisms of immune signaling pathways and develop novel therapeutic strategies for combating infectious and inflammatory conditions. Invest in the MyD88 Monoclonal Antibody today and unlock new possibilities in immune regulation research.
Product Name:
MyD88 Monoclonal Antibody
SKU:
CAB21905
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human MyD88 (NP_002459.3).
This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
4615
Clone Number:
ARC52509
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse lung, using MyD88 Rabbit mAb (CAB21905) at1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
![[KO/KD Validated]MyD88 Rabbit Monoclonal Antibody (CAB22600)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/images/stencil/590x590/products/223322/583859/kokd-validatedmyd88-rabbit-monoclonal-antibody__09830.1701185497.jpg?c=2 "[KO/KD Validated]MyD88 Rabbit Monoclonal Antibody (CAB22600)")
