The MYCL Polyclonal Antibody (CAB16301) is a powerful tool for researchers studying the MYCL protein, a transcription factor involved in cell growth and proliferation. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the MYCL protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it ideal for investigations in cancer biology and molecular biology.
MYCL, a member of the MYC family of oncogenes, is known for its role in promoting cell cycle progression and driving tumorigenesis. Its aberrant expression has been implicated in various types of cancer, making it a promising target for therapeutic interventions. Researchers studying MYCL with this antibody can gain valuable insights into the molecular mechanisms underlying cancer development and potentially identify new treatment strategies.
Product Name:
MYCL Rabbit Polyclonal Antibody
SKU:
CAB16301
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 250-350 of human MYCL (NP_001028253.1).
Sequence:
ALRD QVPT LASC SKAP K
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:1000
Synonyms:
LMYC; L-Myc; MYCL1; bHLHe38; MYCL
Positive Sample:
A-549,BxPC-3
Conjugate:
Unconjugated
Cellular Localization:
Nucleus.
Calculated MW:
40kDa
Observed MW:
40kDa
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of inner ear auditory receptor cell differentiation. Located in chromosome and nucleoplasm.
Purification Method:
Affinity purification
Gene ID:
4610
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MYCL antibody (CAB16301) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
