MYBPC3 Rabbit Polyclonal Antibody (CAB12351)
- SKU:
- CAB12351
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | MYBPC3 Rabbit Polyclonal Antibody |
SKU: | CAB12351 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 200-400 of human MYBPC3 (NP_000247.2). |
Sequence: | SSKV GQHL QLHD SYDR ASKV YLFE LHIT DAQP AFTG SYRC EVST KDKF DCSN FNLT VHEA MGTG DLDL LSAF RRTS LAGG GRRI SDSH EDTG ILDF SSLL KKRD SFRT PRDS KLEA PAEE DVWE ILRQ APPS EYER IAFQ YGVT DLRG MLKR LKGM RRDE KKST AFQK KLEP AYQV SKGH KIRL TVEL ADHD AEVK WLKN G |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | FHC; CMH4; CMD1MM; LVNC10; MYBP-C; cMyBP-C; MYBPC3 |
Positive Sample: | Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | A band, C zone, cardiac myofibril, cytosol, sarcomere, striated muscle myosin thick filament |
Calculated MW: | 141kDa |
Observed MW: | 170kDa |
MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3 is expressed exclusively in heart muscle and is a key regulator of cardiac contraction. Mutations in this gene are a frequent cause of familial hypertrophic cardiomyopathy.
Purification Method: | Affinity purification |
Gene ID: | 4607 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |