The MYBPC3 Antibody (PAC028450) is a high-quality polyclonal antibody specifically designed for research involving the MYBPC3 protein. MYBPC3 is a critical component of cardiac muscle, playing a key role in regulating muscle contraction and relaxation. Mutations in the MYBPC3 gene are associated with various cardiac conditions, making it a valuable target for cardiovascular research.This antibody, raised in rabbits, is highly reactive with human, mouse, and rat samples, making it versatile for use in a variety of experimental settings. It has been validated for use in Western blot applications, providing researchers with a reliable tool for detecting and analyzing MYBPC3 protein levels in cardiac tissue and cell samples.
The MYBPC3 Antibody enables researchers to study the role of MYBPC3 in cardiac function and disease, offering insights into the mechanisms underlying cardiac muscle disorders, such as hypertrophic cardiomyopathy. By understanding the function of MYBPC3 and its contribution to cardiac health, researchers can work towards developing novel therapeutic strategies for treating cardiovascular diseases.
Antibody Name:
Mybpc3 Antibody (PACO28450)
Antibody SKU:
PACO28450
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Rat
Immunogen:
Recombinant Rat Myosin-binding protein C, cardiac-type protein (645-864AA)
Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role.
MYBPC3: Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role. Belongs to the immunoglobulin superfamily. MyBP family.Protein type: Myosin-bindingChromosomal Location of Human Ortholog: 3q24Cellular Component: A band; M band; myofibril; sarcomere; striated muscle thick filament; Z discMolecular Function: actin filament binding; identical protein binding; muscle alpha-actinin binding; myosin binding; myosin heavy chain binding; structural constituent of muscleBiological Process: actin filament organization; cardiac muscle contraction; heart morphogenesis; muscle contraction; myosin filament assembly; regulation of heart contraction; regulation of heart rate; regulation of striated muscle contraction; sarcomere organization; ventricular cardiac muscle morphogenesis
