The MYBPC2 Polyclonal Antibody (CAB6934) is a valuable tool for researchers studying MYBPC2, a gene involved in muscle contraction and development. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By targeting the MYBPC2 protein, this antibody allows for the detection and analysis of MYBPC2 expression in various tissues and cell types, making it a versatile option for studies in muscle biology and related fields.
MYBPC2, also known as myosin binding protein C fast type, plays a crucial role in regulating muscle contraction and sarcomere structure, making it a key player in muscle function. Its involvement in muscle development and maintenance also suggests potential implications in muscle-related disorders and diseases. By delving into the functions of MYBPC2, researchers can gain insights into muscular pathologies and potentially identify new therapeutic targets for muscle-related conditions.
Product Name:
MYBPC2 Rabbit Polyclonal Antibody
SKU:
CAB6934
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 912-1141 of human MYBPC2 (NP_004524.3).
This gene encodes a member of the myosin-binding protein C family. This family includes the fast-, slow- and cardiac-type isoforms, each of which is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. The protein encoded by this locus is referred to as the fast-type isoform. Mutations in the related but distinct genes encoding the slow-type and cardiac-type isoforms have been associated with distal arthrogryposis, type 1 and hypertrophic cardiomyopathy, respectively.
Purification Method:
Affinity purification
Gene ID:
4606
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MYBPC2 antibody (CAB6934) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
