The MYB Polyclonal Antibody (CAB13776) is a valuable tool for researchers studying the MYB gene, a transcription factor known for its role in regulating cell growth and differentiation. Raised in rabbits, this antibody is highly specific to human MYB protein and has been validated for use in Western blot applications. By targeting the MYB protein, this antibody allows for the detection and analysis of MYB expression in various cell types, making it well-suited for research in oncology, hematology, and developmental biology.The MYB gene is involved in controlling the formation and function of blood cells, making it a key player in conditions such as leukemia and other hematological disorders.
Understanding the regulation of MYB expression and activity is essential for investigating the mechanisms underlying these diseases and developing targeted therapies. The MYB Polyclonal Antibody offers researchers a reliable tool for exploring the functions of MYB in both normal and diseased states, paving the way for advancements in personalized medicine and novel treatment strategies.
Product Name:
MYB Rabbit Polyclonal Antibody
SKU:
CAB13776
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 380-640 of human MYB (NP_005366.2).
This gene encodes a protein with three HTH DNA-binding domains that functions as a transcription regulator. This protein plays an essential role in the regulation of hematopoiesis. This gene may be aberrently expressed or rearranged or undergo translocation in leukemias and lymphomas, and is considered to be an oncogene. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
4602
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using MYB Rabbit pAb (CAB13776) at 1:10000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 20s.
