MXD4 Rabbit Polyclonal Antibody (CAB16485)
- SKU:
- CAB16485
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | MXD4 Rabbit Polyclonal Antibody |
SKU: | CAB16485 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 110-209 of human MXD4 (NP_006445.1). |
Sequence: | RRAL SIKE QLQQ EHRF LKRR LEQL SVQS VERV RTDS TGSA VSTD DSEQ EVDI EGME FGPG ELDS VGSS SDAD DHYS LQSG TGGD SGFG PHCR RLGR PALS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | MAD4; MST149; MSTP149; bHLHc12; MXD4 |
Positive Sample: | Mouse lung |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 24kDa |
Observed MW: | 30kDa |
This gene is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues.
Purification Method: | Affinity purification |
Gene ID: | 10608 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |