The MXD1 Polyclonal Antibody (CAB3613) is a vital tool for researchers studying MXD1, a transcription factor known for its role in cell cycle regulation and apoptosis. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the MXD1 protein, this antibody allows for the detection and analysis of MXD1 expression in a variety of cell types, making it an essential component for studies in molecular biology and cancer research.MXD1, also known as Max Dimerization Protein 1, plays a crucial role in controlling cell growth and differentiation by regulating gene transcription. Its involvement in cellular processes makes it a key player in understanding diseases such as cancer, where dysregulation of cell cycle control can lead to uncontrolled cell proliferation.
Research into MXD1 and its functions can provide insights into potential therapeutic targets for cancer treatment and other related conditions.Overall, the MXD1 Polyclonal Antibody (CAB3613) is a valuable tool for researchers looking to investigate the mechanisms by which MXD1 influences cellular pathways and contributes to disease development. Its specificity and reliability make it an essential asset for advancing our understanding of MXD1 biology and its implications for human health.
Product Name:
MXD1 Rabbit Polyclonal Antibody
SKU:
CAB3613
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human MXD1 (NP_002348.1).
This gene encodes a member of the MYC/MAX/MAD network of basic helix-loop-helix leucine zipper transcription factors. The MYC/MAX/MAD transcription factors mediate cellular proliferation, differentiation and apoptosis. The encoded protein antagonizes MYC-mediated transcriptional activation of target genes by competing for the binding partner MAX and recruiting repressor complexes containing histone deacetylases. Mutations in this gene may play a role in acute leukemia, and the encoded protein is a potential tumor suppressor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
4084
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MXD1 antibody (CAB3613) at 1:800 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
