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MX2 Antibody (PACO02915)

SKU:
PACO02915
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€269
Frequently bought together:

Description

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MX2 Antibody (PACO02915)

The MX2 Polyclonal Antibody (PAC02915) is a valuable tool for researchers studying MX2, a critical protein involved in antiviral defense mechanisms. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in various applications, including Western blotting. By specifically binding to the MX2 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential component of studies in virology and infectious diseases.

MX2 is a key player in the host's defense against viral infections, functioning by inhibiting the replication of a broad range of viruses. Understanding the role of MX2 is crucial in developing strategies for combating viral diseases and developing antiviral therapies. Research into MX2 has implications for the fields of virology, immunology, and drug development, as targeting this protein could lead to novel approaches for treating viral infections and improving global public health.

Antibody Name:MX2 Antibody
Antibody SKU:PACO02915
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA
Recommended Dilutions:
Species Reactivity:Human
Immunogen:synthesized peptide derived from the Internal region of human MxB.
Form:Liquid
Storage Buffer:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:MX2; Interferon-induced GTP-binding protein Mx2; Interferon-regulated resistance GTP-binding protein MxB; Myxovirus resistance protein 2; p78-related protein
UniProt Protein Function:MX2: has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This protein is upregulated by interferon-alpha but does not contain the antiviral activity of a similar myxovirus resistance protein 1. [provided by RefSeq, Jul 2008]Protein type: G protein regulator, misc.Chromosomal Location of Human Ortholog: 21q22.3Cellular Component: cytoplasm; nuclear pore; cytosol; nucleusMolecular Function: GTPase activity; GTP bindingBiological Process: protein transport; mRNA transport; metabolic process; regulation of cell cycle; regulation of nucleocytoplasmic transport; cytokine and chemokine mediated signaling pathway; response to virus; defense response; defense response to virus
UniProt Protein Details:
NCBI Summary:The protein encoded by this gene has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This protein is upregulated by interferon-alpha but does not contain the antiviral activity of a similar myxovirus resistance protein 1. [provided by RefSeq, Jul 2008]
UniProt Code:P20592
NCBI GenInfo Identifier:11342664
NCBI Gene ID:4600
NCBI Accession:NP_002454.1
UniProt Secondary Accession:P20592,B7Z5D3, D3DSI7
UniProt Related Accession:P20592
Molecular Weight:
NCBI Full Name:interferon-induced GTP-binding protein Mx2
NCBI Synonym Full Names:MX dynamin-like GTPase 2
NCBI Official Symbol:MX2  
NCBI Official Synonym Symbols:MXB  
NCBI Protein Information:interferon-induced GTP-binding protein Mx2; p78-related protein; myxovirus resistance protein 2; second interferon-induced protein p78; myxovirus (influenza virus) resistance 2; interferon-regulated resistance GTP-binding protein MXB
UniProt Protein Name:Interferon-induced GTP-binding protein Mx2
UniProt Synonym Protein Names:Interferon-regulated resistance GTP-binding protein MxB; Myxovirus resistance protein 2; p78-related protein
Protein Family:Interferon-induced GTP-binding protein
UniProt Gene Name:MX2  
UniProt Entry Name:MX2_HUMAN

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