The MX1 Polyclonal Antibody (CAB1780) is a valuable tool for researchers investigating the MX1 protein, which is involved in antiviral immune responses. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blotting applications. By binding to the MX1 protein, this antibody enables researchers to detect and analyze MX1 expression in a wide range of cell types, making it ideal for studies in virology and infectious disease research.MX1, also known as interferon-induced GTP-binding protein Mx1, plays a crucial role in the antiviral defense mechanism by inhibiting viral replication.
Understanding the function of MX1 is essential for developing effective antiviral therapies and vaccines. Research on MX1 can also provide insights into the mechanisms underlying viral infections and host immune responses, paving the way for new treatment strategies for viral diseases.Overall, the MX1 Polyclonal Antibody (CAB1780) is a valuable research tool for scientists working in the fields of virology, immunology, and infectious diseases. Its high specificity and sensitivity make it a reliable tool for studying the role of MX1 in antiviral immune responses and identifying potential therapeutic targets for viral infections.
Product Name:
MX1 Rabbit Polyclonal Antibody
SKU:
CAB1780
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 200-300 of human MX1 (NP_001171517.1).
This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that participates in the cellular antiviral response. The encoded protein is induced by type I and type II interferons and antagonizes the replication process of several different RNA and DNA viruses. There is a related gene located adjacent to this gene on chromosome 21, and there are multiple pseudogenes located in a cluster on chromosome 4. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
4599
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from Daudi cells, using MX1 Rabbit pAb (CAB1780) at 1:600 dilution.Daudi cells were treated by IFN-α (100 ng/ml) at 37℃ for 30 minutes after serum-starvation overnight.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
