The MVD Polyclonal Antibody (CAB15240) is a valuable tool for research involving the MVD protein, a key enzyme involved in the mevalonate pathway. This pathway plays a critical role in cholesterol biosynthesis, making MVD a target of interest in studies related to lipid metabolism, cardiovascular disease, and cancer.This rabbit polyclonal antibody is highly specific to human MVD and has been validated for use in Western blot applications, allowing for accurate detection and analysis of MVD protein levels in various cell types. By targeting the MVD protein, researchers can gain insights into its function and potential role in disease processes, providing a better understanding of its implications in health and pathology.
Given the importance of the mevalonate pathway in several physiological and pathological processes, the MVD Polyclonal Antibody is a valuable tool for researchers exploring potential therapeutic targets in conditions such as atherosclerosis, cancer, and metabolic disorders. Its high reactivity and specificity make it a reliable choice for studies seeking to unravel the complexities of MVD and its impact on human health.
Product Name:
MVD Rabbit Polyclonal Antibody
SKU:
CAB15240
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human MVD (NP_002452.1).
The enzyme mevalonate pyrophosphate decarboxylase catalyzes the conversion of mevalonate pyrophosphate into isopentenyl pyrophosphate in one of the early steps in cholesterol biosynthesis. It decarboxylates and dehydrates its substrate while hydrolyzing ATP.
Purification Method:
Affinity purification
Gene ID:
4597
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MVD Rabbit pAb (CAB15240) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
