The MVB12A Polyclonal Antibody (CAB15930) is a vital tool for researchers studying MVB12A, a protein involved in the endosomal sorting complex required for transport (ESCRT) pathway. This antibody, generated in rabbits, exhibits strong reactivity with human samples and is validated for use in Western blot applications. By specifically targeting the MVB12A protein, researchers can accurately detect and analyze its expression in various cell types, making it a valuable asset for studies in cell biology and molecular biology.MVB12A is a critical component of the ESCRT machinery, playing a key role in membrane remodeling and protein sorting processes within the cell.
Dysfunction of the ESCRT pathway has been linked to various diseases, including cancer, neurodegenerative disorders, and viral infections. By investigating the function of MVB12A, researchers can gain insight into the mechanisms underlying these conditions and potentially identify new therapeutic targets for intervention. Unlocking the secrets of MVB12A's role in cellular pathways could lead to significant advancements in biomedical research and drug development efforts.
Product Name:
MVB12A Rabbit Polyclonal Antibody
SKU:
CAB15930
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-273 of human MVB12A (NP_612410.1).
Enables lipid binding activity and ubiquitin binding activity. Involved in regulation of epidermal growth factor receptor signaling pathway; viral budding; and virus maturation. Located in several cellular components, including Golgi apparatus; centrosome; and nucleoplasm. Part of ESCRT I complex.
Purification Method:
Affinity purification
Gene ID:
93343
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse liver, using MVB12A Rabbit pAb (CAB15930) at 1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 10s.
