The Multimerin-1 Polyclonal Antibody (CAB6658) is a valuable tool for researchers studying Multimerin-1, a glycoprotein involved in platelet aggregation and blood clotting. This antibody, produced in rabbits, exhibits high specificity and sensitivity to human Multimerin-1, making it a reliable choice for Western blot applications.Multimerin-1 is important in the regulation of hemostasis and thrombosis, and its dysregulation has been linked to various bleeding disorders and cardiovascular diseases. By targeting Multimerin-1 with this antibody, researchers can explore its role in these physiological processes and potentially identify new therapeutic targets for clotting disorders.Furthermore, the Multimerin-1 Polyclonal Antibody (CAB6658) offers researchers the opportunity to investigate Multimerin-1's potential involvement in cancer progression, as aberrant expression of this protein has been observed in certain cancer types.
With this antibody, researchers can delve into the mechanisms underlying Multimerin-1's contribution to cancer development and potentially uncover novel strategies for cancer treatment.In conclusion, the Multimerin-1 Polyclonal Antibody (CAB6658) is a versatile tool for researchers interested in unraveling the functions of Multimerin-1 in both physiological and pathological conditions. Its high reactivity and specificity make it an indispensable resource for studies in hemostasis, thrombosis, cardiovascular diseases, and cancer research.
Product Name:
MMRN1 Rabbit Polyclonal Antibody
SKU:
CAB6658
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1083-1228 of human MMRN1 (NP_031377.2).
Multimerin is a massive, soluble protein found in platelets and in the endothelium of blood vessels. It is comprised of subunits linked by interchain disulfide bonds to form large, variably sized homomultimers. Multimerin is a factor V/Va-binding protein and may function as a carrier protein for platelet factor V. It may also have functions as an extracellular matrix or adhesive protein. Recently, patients with an unusual autosomal-dominant bleeding disorder (factor V Quebec) were found to have a deficiency of platelet multimerin.
Purification Method:
Affinity purification
Gene ID:
22915
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using MMRN1 Rabbit pAb (CAB6658) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Negative control (NC):U-251 MGExposure time: 180s.
