The MUC5A Polyclonal Antibody (CAB17325) is a valuable tool for researchers studying mucin 5A (MUC5A), a protein found in mucous secretions of the respiratory and gastrointestinal tracts. This antibody, produced in rabbits, exhibits high specificity for human samples and is suitable for Western blot analysis. By binding to the MUC5A protein, this antibody enables detection and characterization of MUC5A in various cell types, making it ideal for research in respiratory and gastrointestinal physiology, as well as studies on mucin-related diseases such as cystic fibrosis and chronic obstructive pulmonary disease.
MUC5A, a major component of mucus, plays a crucial role in protecting and lubricating epithelial surfaces in the body. Dysregulation of MUC5A expression and function has been linked to various respiratory and gastrointestinal disorders, highlighting its importance in maintaining physiological homeostasis. By investigating the role of MUC5A using this antibody, researchers can gain valuable insights into the pathophysiology of mucin-related diseases and potentially identify new therapeutic targets for intervention.
Product Name:
MUC5A Rabbit Polyclonal Antibody
SKU:
CAB17325
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1550-1900 of human Mucin 5AC (MUC5AC) (NP_001291288.1).
Predicted to be an extracellular matrix structural constituent. Involved in phosphatidylinositol-mediated signaling. Located in cytoplasm; extracellular space; and mucus layer. Implicated in dry eye syndrome. Biomarker of several diseases, including Sjogren's syndrome; biliary tract disease (multiple); cystic fibrosis; eye disease (multiple); and pancreatic cancer (multiple).
Purification Method:
Affinity purification
Gene ID:
4586
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of Mouse stomach, using Mucin 5AC (MUC5AC) antibody (CAB17325) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
