The MUC20 Polyclonal Antibody (CAB15968) is a valuable tool for researchers studying MUC20, a mucin protein known for its involvement in various diseases, including cancer. This antibody, produced in rabbits, is specifically designed to target MUC20 in human samples and has been validated for use in Western blot applications. By binding to the MUC20 protein, this antibody enables precise detection and analysis in different cell types, making it an ideal choice for research in oncology and mucin biology.
MUC20 is a mucin protein associated with cell adhesion and signaling pathways, playing a crucial role in cancer progression and metastasis. Understanding the function and regulation of MUC20 can provide insights into the development of new diagnostic tools and targeted therapies for cancer patients. The MUC20 Polyclonal Antibody offers researchers a reliable tool to further explore the role of MUC20 in health and disease, ultimately leading to advancements in cancer treatment strategies.
Product Name:
MUC20 Rabbit Polyclonal Antibody
SKU:
CAB15968
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human MUC20 (NP_689886.3).
This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins secreted by many epithelial tissues to form an insoluble mucous barrier. The C-terminus of this family member associates with the multifunctional docking site of the MET proto-oncogene and suppresses activation of some downstream MET signaling cascades. The protein features a mucin tandem repeat domain that varies between two and six copies in most individuals. Multiple variants encoding different isoforms have been found for this gene. A related pseudogene, which is also located on chromosome 3, has been identified.
Purification Method:
Affinity purification
Gene ID:
200958
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MUC20 Rabbit pAb (CAB15968) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
