MUC15 Antibody (PACO14076)
- SKU:
- PACO14076
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
MUC15 Antibody (PACO14076)
The MUC15 Polyclonal Antibody (PAC014076) is a valuable tool for research involving MUC15, a cell surface mucin protein involved in cell adhesion and signaling. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in applications such as Western blot and immunohistochemistry.MUC15 is known to play a role in various physiological and pathological processes, including cancer progression and metastasis. As a cell surface glycoprotein, it is involved in cell-cell interactions and may contribute to the invasive properties of cancer cells.
Research on MUC15 is crucial for understanding its function in disease development and progression.By using the MUC15 Polyclonal Antibody, researchers can study the expression and localization of MUC15 in different cell types and tissues, allowing for insights into its role in cancer biology and other conditions. This antibody is a valuable resource for studying the function and regulation of MUC15 and its potential as a therapeutic target in cancer research.
| Antibody Name: | MUC15 Antibody (PACO14076) |
| Antibody SKU: | PACO14076 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
| Species Reactivity: | Human |
| Immunogen: | Fusion protein of human MUC15 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO14076(MUC15 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO14076(MUC15 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | Mucins are a family of high molecular weight, heavily glycosylated proteins (glycoconjugates) produced by epithelial tissues in most metazoans. Mucin 15 is involved in cell adhesion to the extracellular matrix. It is primarily expressed in prostate, testis, lung, spleen, thymus, ovary, small intestine, colon, bone marrow, lymph node, lung and peripheral blood leukocytes. Mucin 15 is a highly glycosylated protein. |
| Synonyms: | mucin 15, cell surface associated |
| UniProt Protein Function: | MUC15: May play a role in the cell adhesion to the extracellular matrix. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cell adhesion; Membrane protein, integral Chromosomal Location of Human Ortholog: 11p14.3 Cellular Component: Golgi lumen Biological Process: O-glycan processing |
| UniProt Code: | Q8N387 |
| NCBI GenInfo Identifier: | 84028223 |
| NCBI Gene ID: | 143662 |
| NCBI Accession: | Q8N387.2 |
| UniProt Secondary Accession: | Q8N387,Q6UWS3, Q8IXI8, Q8WW41, B3KY00, E9PII6, F8W945 |
| UniProt Related Accession: | Q8N387 |
| Molecular Weight: | 30,762 Da |
| NCBI Full Name: | Mucin-15 |
| NCBI Synonym Full Names: | mucin 15, cell surface associated |
| NCBI Official Symbol: | MUC15Â Â |
| NCBI Official Synonym Symbols: | PAS3; MUC-15; PASIIIÂ Â |
| NCBI Protein Information: | mucin-15 |
| UniProt Protein Name: | Mucin-15 |
| Protein Family: | Mucin |
| UniProt Gene Name: | MUC15Â Â |
| UniProt Entry Name: | MUC15_HUMAN |
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