The MUC13 Antibody (PACO18719) is a highly specific and sensitive tool for researchers investigating the role of MUC13, a cell surface mucin glycoprotein, in various biological processes. This polyclonal antibody, produced in rabbits, is compatible with human samples and has been validated for use in Western blot applications. By targeting the MUC13 protein, this antibody enables accurate detection and analysis of MUC13 expression in different cell types, making it an ideal choice for studies in cell biology, cancer biology, and mucin research.MUC13 is known to play a crucial role in cell signaling, adhesion, and protection of epithelial tissues, making it a particularly interesting target for research in cancer progression and metastasis.
Its aberrant expression has been linked to various types of cancer, suggesting its potential as a biomarker or therapeutic target in oncology. By elucidating the function of MUC13, researchers can gain valuable insights into the mechanisms underlying tumor development and identify new avenues for cancer treatment.Overall, the MUC13 Antibody (PACO18719) offers researchers a valuable tool for studying the biological functions and clinical implications of MUC13, advancing our understanding of its role in human health and disease.
Antibody Name:
MUC13 Antibody (PACO18719)
Antibody SKU:
PACO18719
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:25-1:100
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human MUC13
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO18719(MUC13 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO18719(MUC13 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
Epithelial mucins, such as MUC13, are a family of secreted and cell surface glycoproteins expressed by ductal and glandular epithelial tissues (
Synonyms:
mucin 13, cell surface associated
UniProt Protein Function:
Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling.
NCBI Summary:
Epithelial mucins, such as MUC13, are a family of secreted and cell surface glycoproteins expressed by ductal and glandular epithelial tissues (Williams et al., 2001 [PubMed 11278439]).[supplied by OMIM, Jul 2008]