The MUC13 Polyclonal Antibody (PAC018718) is a valuable tool for researchers studying MUC13, a mucin protein that plays a role in cell adhesion and signaling. This antibody, produced in rabbits, exhibits high specificity and reactivity towards human samples, making it a reliable choice for experiments in immunohistochemistry and flow cytometry.MUC13 is known to be overexpressed in various cancers, including colorectal and pancreatic cancer, and has been implicated in promoting tumor growth and metastasis. By targeting MUC13 with this antibody, researchers can investigate its function in cancer development and progression, potentially leading to the identification of novel therapeutic targets.
With its high specificity and proven performance in various experimental applications, the MUC13 Polyclonal Antibody is a valuable tool for scientists conducting research in cancer biology, cell biology, and mucin biology. Its ability to detect and analyze MUC13 expression in different cell types makes it a versatile reagent for advancing our understanding of the role of mucins in health and disease.
Antibody Name:
MUC13 Antibody (PACO18718)
Antibody SKU:
PACO18718
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:1000-1:2000, IHC:1:15-1:50
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human MUC13
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO18718(MUC13 Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
Epithelial mucins, such as MUC13, are a family of secreted and cell surface glycoproteins expressed by ductal and glandular epithelial tissues (
Synonyms:
mucin 13, cell surface associated
UniProt Protein Function:
Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling.
NCBI Summary:
Epithelial mucins, such as MUC13, are a family of secreted and cell surface glycoproteins expressed by ductal and glandular epithelial tissues (Williams et al., 2001 [PubMed 11278439]).[supplied by OMIM, Jul 2008]
