The MUC13 Polyclonal Antibody (PACO06661) is a valuable tool for researchers studying MUC13, a transmembrane glycoprotein involved in cell signaling and adhesion. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in various applications, including Western blot and immunohistochemistry.MUC13 plays a critical role in cell proliferation, survival, and migration, making it a key player in cancer progression and metastasis. Its overexpression has been linked to poor prognosis in several types of cancer, making it a promising target for cancer therapy development.
By using the MUC13 Polyclonal Antibody, researchers can investigate the expression levels and localization of MUC13 in different cell types and tissues, providing valuable insights into its role in cancer biology.Furthermore, understanding the function of MUC13 can also have implications in inflammatory disorders and other diseases related to abnormal cell adhesion and signaling. The MUC13 Polyclonal Antibody is a reliable tool for researchers interested in unraveling the complex biology of MUC13 and its potential therapeutic implications.
Synthesized peptide derived from the C-terminal region of human Mucin 13.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western Blot analysis of L929 cells using Mucin 13 Polyclonal Antibody.
Western Blot analysis of COLO205 cells using Mucin 13 Polyclonal Antibody.
Synonyms:
MUC13; DRCC1; RECC; Mucin-13; MUC-13; Down-regulated in colon cancer 1
UniProt Protein Function:
Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling.
NCBI Summary:
Epithelial mucins, such as MUC13, are a family of secreted and cell surface glycoproteins expressed by ductal and glandular epithelial tissues (Williams et al., 2001 [PubMed 11278439]).[supplied by OMIM, Jul 2008]
