The MTUS1 Polyclonal Antibody (CAB13437) is a valuable tool for researchers studying MTUS1, a tumor suppressor gene implicated in cancer development and progression. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blotting applications. By binding specifically to the MTUS1 protein, this antibody enables researchers to detect and analyze MTUS1 expression in various cell types, making it an ideal choice for studies in oncology and molecular biology.MTUS1, also known as angiotensin-II receptor-interacting protein 4, plays a crucial role in controlling cell proliferation, migration, and apoptosis, making it a key player in tumorigenesis.
Understanding the function and regulation of MTUS1 is essential for identifying new therapeutic targets and developing treatments for various cancers. The MTUS1 Polyclonal Antibody provides a reliable tool for investigating the role of MTUS1 in cancer biology and may lead to novel insights into cancer pathogenesis and treatment strategies.
Product Name:
MTUS1 Rabbit Polyclonal Antibody
SKU:
CAB13437
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 207-436 of human MTUS1 (NP_065800.1).
This gene encodes a protein which contains a C-terminal domain able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other variants may encode nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways.
Purification Method:
Affinity purification
Gene ID:
57509
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of SH-SY5Y cells, using MTUS1 antibody (CAB13437) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
