The MTTP Polyclonal Antibody (CAB14028) is a valuable tool for researchers studying microsomal triglyceride transfer protein (MTTP), a crucial enzyme involved in lipid metabolism and the assembly and secretion of lipoproteins like chylomicrons and very low-density lipoproteins (VLDL). Raised in rabbits, this antibody is highly specific to human samples and has been validated for use in Western blot applications.MTTP plays a key role in lipid transport and metabolism, making it a target of interest in studies related to cardiovascular disease, obesity, and metabolic disorders.
By binding to MTTP, this antibody allows for the detection and analysis of MTTP expression in various cell types, making it an ideal tool for researchers in biochemistry, metabolism, and lipid biology.Understanding the function and regulation of MTTP is important for unraveling the mechanisms underlying lipid-related diseases and developing targeted therapies to treat or prevent these conditions. The MTTP Polyclonal Antibody (CAB14028) provides researchers with a reliable tool to advance their research in this field.
Product Name:
MTTP Rabbit Polyclonal Antibody
SKU:
CAB14028
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 19-160 of human MTTP (NP_000244.2).
MTP encodes the large subunit of the heterodimeric microsomal triglyceride transfer protein. Protein disulfide isomerase (PDI) completes the heterodimeric microsomal triglyceride transfer protein, which has been shown to play a central role in lipoprotein assembly. Mutations in MTP can cause abetalipoproteinemia.
Purification Method:
Affinity purification
Gene ID:
4547
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using MTTP Rabbit pAb (CAB14028) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
